Menthyl esterification allows chiral resolution for the synthesis of artificial glutamate analogs

• Kenji Morokuma,
• Shuntaro Tsukamoto,
• Kyosuke Mori,
• Kei Miyako,
• Ryuichi Sakai,
• Raku Irie and
• Masato Oikawa

Beilstein J. Org. Chem. 2021, 17, 540–550, doi:10.3762/bjoc.17.48

• challenging [15][16], and this was also the case for (rac)-13, since we first obtained the incomplete triene intermediate (rac)-15 as a result of only ring-opening metathesis (ROM) mediated by the Fischer carbene complex [Ru]=CH–OAc [6], generated by the reaction of Zhan catalyst-1B (14) with vinyl acetate

On the mechanism of imine elimination from Fischer tungsten carbene complexes

• Philipp Veit,
• Christoph Förster and
• Katja Heinze

Beilstein J. Org. Chem. 2016, 12, 1322–1333, doi:10.3762/bjoc.12.125

• Since the first example of a Fischer carbene complex (CO)5W=C(OMe)Me [1] in 1964, these compounds have evolved into a huge substance class with versatile applications as chemical multitalents in organic synthesis [2][3][4][5] as well as in light-driven organic reactions [6][7][8]. Carbene complexes of

Selected synthetic strategies to cyclophanes

• Sambasivarao Kotha,
• Mukesh E. Shirbhate and
• Gopalkrushna T. Waghule

Beilstein J. Org. Chem. 2015, 11, 1274–1331, doi:10.3762/bjoc.11.142

• benzannulation as a key step. They found that the Fischer carbene complex 314 in a coordinating solvent such as THF lead to the products 312 (15%) and 313 (42%) whereas a non-coordinating solvent like benzene delivered products 315 (40%) and 316 (21%, Scheme 54). Wulff and Wang [190] have synthesized [6,6

• ]metacyclophane via an intermolecular benzannulation reaction of Fischer carbene complexes with a residual alkyne to generate the 18-membered ring. Two molecules of the Fischer carbene complex 317 reacted by an intermolecular fashion to generate the [6,6]metacyclophane 318 (39%). Alternatively, a double

One-pot three-component synthesis of quinoxaline and phenazine ring systems using Fischer carbene complexes

• Priyabrata Roy and
• Binay Krishna Ghorai

Beilstein J. Org. Chem. 2010, 6, No. 52, doi:10.3762/bjoc.6.52

• . Keywords: azaisobenzofuran; Diels–Alder; Fischer carbene complex; phenazine; quinoxaline; Introduction Nitrogen-containing heterocycles are abundant in nature and exhibit diverse and important biological properties [1]. Quinoxaline and phenazine derivatives are important classes of nitrogen containing

• carbonyl derivatives 1A/1B with simple γ,δ-unsaturated Fischer carbene complex 10 was investigated. This reaction proceeds via a tandem process involving the formation of azaisobenzofuran 11, followed by intramolecular Diels–Alder reaction, and ring opening of 12 to afford azahydrophenanthrone derivatives